Baseline and early changes in laboratory parameters predict disease severity and fatal outcomes in COVID-19 patients

Autor: Addisu Gize, Yerega Belete, Melkayehu Kassa, Wondewosen Tsegaye, Gadissa Bedada Hundie, Birhan Mesele Belete, Mahteme Bekele, Berhan Ababaw, Yosef Tadesse, Bereket Fantahun, Sisay Sirgu, Solomon Ali, Anteneh Mehari Tizazu
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Frontiers in Public Health, Vol 11 (2023)
Druh dokumentu: article
ISSN: 2296-2565
DOI: 10.3389/fpubh.2023.1252358
Popis: IntroductionCoronavirus disease 2019 (COVID-19) has become the worst catastrophe of the twenty-first century and has led to the death of more than 6.9 million individuals across the globe. Despite the growing knowledge of the clinicopathological features of COVID-19, the correlation between baseline and early changes in the laboratory parameters and the clinical outcomes of patients is not entirely understood.MethodsHere, we conducted a time series cross-sectional study aimed at assessing different measured parameters and socio-demographic factors that are associated with disease severity and the outcome of the disease in 268 PCR-confirmed COVID-19 Patients.ResultsWe found COVID-19 patients who died had a median age of 61 years (IQR, 50 y – 70 y), which is significantly higher (p
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