Autor: |
Shah Nirav K., Shah Nimesh M., Patel Manish P., Patel Ranjan G. |
Jazyk: |
angličtina |
Rok vydání: |
2012 |
Předmět: |
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Zdroj: |
Journal of the Serbian Chemical Society, Vol 77, Iss 3, Pp 279-286 (2012) |
Druh dokumentu: |
article |
ISSN: |
0352-5139 |
DOI: |
10.2298/JSC110630197S |
Popis: |
A simple and efficient method has been developed for the synthesis of some novel biquinoline derivatives bearing a thiazole moiety through a onepot three-component condensation of 2-chlro-3-formylquinolines, ethyl cyanoacetate and β-enaminone using catalytic amount of piperidine in refluxing ethanol. These molecules were evaluated in vitro for their antibacterial and antifungal activity. Most of the compounds exhibited moderate antibacterial and antifungal activity against all the tested strains. |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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