Identification of Anaplasma marginale, Babesia bovis and Babesia bigemina resistance alleles in Crioulo Lageano cattle using PCR-SBT and BoLA-DRB3 gene sequencing

Autor: Mariana da Silva Casa, Guillermo Giovambattista, Graziela Vieira Fonteque, Ellen Lara Miguel, Carla Ivane Ganz Vogel, Luiz Claudio Miletti, Shin-Nosuke Takeshima, Joandes Henrique Fonteque
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Frontiers in Veterinary Science, Vol 10 (2023)
Druh dokumentu: article
ISSN: 2297-1769
DOI: 10.3389/fvets.2023.1256928
Popis: IntroductionThe BoLA-DRB3 gene in cattle is associated with tolerance to several infectious diseases, such as neosporosis, dermatophilosis, leukosis, and mastitis.MethodsThis study used PCR-SBT and BoLA-DRB3 gene sequencing to determine the association between the presence or absence of Anaplasma marginale, Babesia bovis, and Babesia bigemina infections in 208 Crioulo Lageano cattle and alleles present in the population. The chi-square test and odds ratio analysis were employed to establish the association.ResultsOf the BoLA-DRB3 gene alleles present in the population, two alleles were significantly associated with resistance to A. marginale infections: BoLA-DRB3001:01 (p
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