Multiple lifestyle factors and depressed mood: a cross-sectional and longitudinal analysis of the UK Biobank (N = 84,860)

Autor: Jerome Sarris, Russell Thomson, Fiona Hargraves, Melissa Eaton, Michael de Manincor, Nicola Veronese, Marco Solmi, Brendon Stubbs, Alison R. Yung, Joseph Firth
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: BMC Medicine, Vol 18, Iss 1, Pp 1-10 (2020)
Druh dokumentu: article
ISSN: 1741-7015
17442869
DOI: 10.1186/s12916-020-01813-5
Popis: Abstract Background There is now evolving data exploring the relationship between depression and various individual lifestyle factors such as diet, physical activity, sleep, alcohol intake, and tobacco smoking. While this data is compelling, there is a paucity of longitudinal research examining how multiple lifestyle factors relate to depressed mood, and how these relations may differ in individuals with major depressive disorder (MDD) and those without a depressive disorder, as ‘healthy controls’ (HC). Methods To this end, we assessed the relationships between 6 key lifestyle factors (measured via self-report) and depressed mood (measured via a relevant item from the Patient Health Questionnaire) in individuals with a history of or current MDD and healthy controls (HCs). Cross-sectional analyses were performed in the UK Biobank baseline sample, and longitudinal analyses were conducted in those who completed the Mental Health Follow-up. Results Cross-sectional analysis of 84,860 participants showed that in both MDD and HCs, physical activity, healthy diet, and optimal sleep duration were associated with less frequency of depressed mood (all p
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