Association of maternal mineral status with the risk of preterm birth: a retrospective cohort study

Autor: Sumiao Hong, Nan Jiang, Guankai Lin, Quqing Wang, Xiaoyang Xu, Xinrui Shi, You Zhou, Xiaoting Wen, Baochang Sun, Hexing Wang, Min Huang, Jiwei Wang, Na Wang, Yue Chen, Qingwu Jiang
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Frontiers in Nutrition, Vol 11 (2024)
Druh dokumentu: article
ISSN: 2296-861X
DOI: 10.3389/fnut.2024.1329720
Popis: BackgroundThere has been a gradual increase in the proportion of preterm birth in China during the past several decades. Maternal malnutrition is a significant determinant for preterm birth. Nevertheless, comprehensive studies investigating serum mineral levels during pregnancy associated with preterm birth remain scarce. This study aims to assess the associations between maternal serum mineral levels and the risk of preterm birth.MethodsThis retrospective cohort study of 18,048 pregnant women used data from a tertiary hospital in China from January 2016 to December 2022. Demographic data and serum mineral concentrations in the second and third trimesters of mothers were collected from the hospital information system. Analysis was performed using restricted cubic splines and logistic regression models.ResultsThe proportion of preterm birth in this study was 6.01%. Phosphorus [P for overall = 0.005; P for nonlinear = 0.490; OR (95%CI) = 1.11 (1.04, 1.18)] and chlorine [P for overall = 0.002; P for nonlinear = 0.058; OR (95%CI) = 1.11 (1.03, 1.19)] showed a significant positive correlation with preterm birth in a linear fashion. Furthermore, serum levels of potassium (P for nonlinear
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