Invasive Burkholderia cepacia Complex Infections among Persons Who Inject Drugs, Hong Kong, China, 2016–2019

Autor: Kristine Shik Luk, Yat-ming Tsang, Alex Yat-man Ho, Wing-kin To, Ben Kwok-ho Wong, Maureen Mo-lin Wong, Yiu-chung Wong
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Emerging Infectious Diseases, Vol 28, Iss 2, Pp 323-330 (2022)
Druh dokumentu: article
ISSN: 1080-6040
1080-6059
DOI: 10.3201/eid2802.210945
Popis: During March 2016–January 2019, Burkholderia cepacia complex (BCC) infection developed in 13 persons who inject drugs (PWID) in Kowloon West Region, Hong Kong, China. Seven cases were infective spondylitis, 2 endocarditis, 2 septic arthritis, 1 intramuscular abscess and bacteremia, and 1 necrotizing fasciitis. Pulsed-field gel electrophoresis revealed that the isolates from 9 patients were clonally related. This clone caused major illness, and 11 of the 13 patients required surgical treatment. Clinicians should be aware of this pathogen and the appropriate broad-spectrum antimicrobial drugs to empirically prescribe for PWID with this life-threatening infection. Close collaboration among public health authorities, outreach social workers, and methadone clinics is essential for timely prevention and control of outbreaks in the PWID population.
Databáze: Directory of Open Access Journals