Hepatoprotective studies on methanolic extract of whole plant of Lindernia ciliata

Autor: Pallerla Praneetha, Vanapatla Swaroopa Rani, Yellu Narasimha Reddy, Bobbala Ravi Kumar
Jazyk: angličtina
Rok vydání: 2014
Předmět:
Zdroj: Bangladesh Journal of Pharmacology, Vol 9, Iss 4 (2014)
Druh dokumentu: article
ISSN: 1991-0088
Popis: Lindernia ciliata is traditionally used in the treatment of jaundice. In the present study, the methanolic extract of L. ciliata was evaluated for its hepatoprotective activity in paracetamol, ethanol and D-galactosamine intoxicated rats. The activity of the extract was assessed on the basis of improvement in the altered level of various serum biochemical parameters and in the changes occurred in the histology of liver of the rats. The extract was also investigated for its antioxidant potential by employing different in vitro methods. Among the three test doses of extract, 200 mg/kg was found to be the most effective dose. The significant (p
Databáze: Directory of Open Access Journals