An epidemic Zika virus isolate suppresses antiviral immunity by disrupting antigen presentation pathways

Autor: Ryan D. Pardy, Stefanie F. Valbon, Brendan Cordeiro, Connie M. Krawczyk, Martin J. Richer
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-021-24340-0
Popis: The CD8 T cell response to Zika virus is known to be a critical component of the host immune response to infection. Here the authors show a Zika virus isolate specific disruption of antigen processing that impacts the host response and impairs viral clearance providing evidence of isolate specific impacts on the immune response to infection
Databáze: Directory of Open Access Journals