Risk of Recurrent Venous Thromboembolism in Selected Subgroups of Men: A Danish Nationwide Cohort Study

Autor: Ida Ehlers Albertsen, Stavros V. Konstantinides, Gregory Piazza, Samuel Z. Goldhaber, Torben Bjerregaard Larsen, Mette Søgaard, Peter Brønnum Nielsen
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: TH Open, Vol 06, Iss 04, Pp e378-e386 (2022)
Druh dokumentu: article
ISSN: 2512-9465
DOI: 10.1055/a-1949-9404
Popis: Background Although men are considered at high risk for recurrent venous thromboembolism (VTE), sex-specific data on prognostic factors are lacking. We estimated the cumulative recurrence risks associated with clinical characteristics and comorbidities known or suspected to be associated with the development of VTE recurrence: major surgery, trauma, history of cancer, rheumatic disorder, ischemic heart disease, congestive heart failure, chronic obstructive pulmonary disease, diabetes, chronic renal disease, varicose veins, alcohol-related diseases, and arterial hypertension. Methods We linked nationwide Danish health registries to identify all incident VTE in- and outpatients in men from 2008 through 2018. Recurrent VTE risk 2 years after anticoagulant discontinuation was calculated using the Aalen-Johansen estimator, stratified by age above/below 50 years. Results The study included 13,932 men with VTE, of whom 21% (n = 2,898) were aged
Databáze: Directory of Open Access Journals