| Autor: |
Sophie Stenton, Jo McPartland, Rajeev Shukla, Kerry Turner, Tamas Marton, Beata Hargitai, Andrew Bamber, Jeremy Pryce, Cesar L Peres, Nadia Burguess, Bart Wagner, Barbara Ciolka, William Simmons, Daniel Hurrell, Thivya Sekar, Corina Moldovan, Claire Trayers, Victoria Bryant, Liina Palm, Marta C Cohen |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
EClinicalMedicine, Vol 47, Iss , Pp 101389- (2022) |
| Druh dokumentu: |
article |
| ISSN: |
2589-5370 |
| DOI: |
10.1016/j.eclinm.2022.101389 |
| Popis: |
Summary: Background: Pregnant women with SARS-CoV-2 infection experience higher rates of stillbirth and preterm birth. A unique pattern of chronic histiocytic intervillositis (CHI) and/or massive perivillous fibrin deposition (MPFD) has emerged, coined as SARS-CoV-2 placentitis. Methods: The aim of this study was to describe a cohort of placentas diagnosed with SARS-CoV-2 placentitis during October 2020-March 2021. Cases with a histological diagnosis of SARS-CoV-2 placentitis and confirmatory immunohistochemistry were reported. Maternal demographic data, pregnancy outcomes and placental findings were collected. Findings: 59 mothers delivered 61 infants with SARS-CoV-2 placentitis. The gestational age ranged from 19 to 41 weeks with most cases (78.6%) being third trimester. 30 infants (49.1%) were stillborn or late miscarriages. Obese mothers had higher rates of pregnancy loss when compared with those with a BMI |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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