Comparative genomic analysis revealed genetic divergence between Bifidobacterium catenulatum subspecies present in infant versus adult guts

Autor:	Jiaqi Liu, Weicheng Li, Caiqing Yao, Jie Yu, Heping Zhang
Jazyk:	angličtina
Rok vydání:	2022
Předmět:	Bifidobacterium catenulatum Genomics Carbohydrate utilization Plant-derived glycan Human milk oligosaccharides Microbiology QR1-502
Zdroj:	BMC Microbiology, Vol 22, Iss 1, Pp 1-14 (2022)
Druh dokumentu:	article
ISSN:	1471-2180
DOI:	10.1186/s12866-022-02573-3
Popis:	Abstract Background The two subspecies of Bifidobacterium catenulatum, B. catenulatum subsp. kashiwanohense and B. catenulatum subsp. catenulatum, are usually from the infant and adult gut, respectively. However, the genomic analysis of their functional difference and genetic divergence has been rare. Here, 16 B. catenulatum strains, including 2 newly sequenced strains, were analysed through comparative genomics. Results A phylogenetic tree based on 785 core genes indicated that the two subspecies of B. catenulatum were significantly separated. The comparison of genomic characteristics revealed that the two subspecies had significantly different genomic sizes (p
Databáze:	Directory of Open Access Journals
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