Invasive Nocardia Infections across Distinct Geographic Regions, United States
| Autor: | Simran Gupta, Leah M. Grant, Harry R. Powers, Kathryn E. Kimes, Ahmed Hamdi, Richard J. Butterfield, Juan Gea-Banacloche, Prakhar Vijayvargiya, D. Jane Hata, Diana M. Meza Villegas, Adrian C. Dumitrascu, Dana M. Harris, Razvan M. Chirila, Nan Zhang, Raymund R. Razonable, Shimon Kusne, Salvador Alvarez, Holenarasipur R. Vikram |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2023 |
| Předmět: | |
| Zdroj: | Emerging Infectious Diseases, Vol 29, Iss 12, Pp 2417-2425 (2023) |
| Druh dokumentu: | article |
| ISSN: | 1080-6040 1080-6059 |
| DOI: | 10.3201/eid2912.230673 |
| Popis: | We reviewed invasive Nocardia infections in 3 noncontiguous geographic areas in the United States during 2011–2018. Among 268 patients with invasive nocardiosis, 48.2% were from Minnesota, 32.4% from Arizona, and 19.4% from Florida. Predominant species were N. nova complex in Minnesota (33.4%), N. cyriacigeorgica in Arizona (41.4%), and N. brasiliensis in Florida (17.3%). Transplant recipients accounted for 82/268 (30.6%) patients overall: 14 (10.9%) in Minnesota, 35 (40.2%) in Arizona, and 33 (63.5%) in Florida. Manifestations included isolated pulmonary nocardiosis among 73.2% of transplant and 84.4% of non–transplant patients and central nervous system involvement among 12.2% of transplant and 3.2% of non–transplant patients. N. farcinica (20.7%) and N. cyriacigeorgica (19.5%) were the most common isolates among transplant recipients and N. cyriacigeorgica (38.0%), N. nova complex (23.7%), and N. farcinica (16.1%) among non–transplant patients. Overall antimicrobial susceptibilities were similar across the 3 study sites. |
| Databáze: | Directory of Open Access Journals |
| Externí odkaz: |
|