Efficient Microwave-Assisted Synthesis of Ionic Esterified Amino Acids

Autor: Frisia Cuellar, Eugenio A. Flores, Luisa E. Montiel, Jorge Aburto, Ricardo Cerón-Camacho, Rafael Martínez-Palou
Jazyk: angličtina
Rok vydání: 2011
Předmět:
Zdroj: Molecules, Vol 16, Iss 10, Pp 8733-8744 (2011)
Druh dokumentu: article
ISSN: 1420-3049
DOI: 10.3390/molecules16108733
Popis: In this work, an efficient microwave-assisted methodology for the esterification of unprotected α-amino acids is described. Ionic esterified amino acids were synthesized in satisfactory yields in a facile one-pot solventless protocol from unprotected amino acids and alcohols under acid catalysis (MsOH or p-TsOH) to afford the pure products after a simple work-up procedure. This procedure can also be extended to the preparation of long and short chain alkyl and benzyl esters.
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