Isolation and characterization of phenolic compounds from Rhodiola imbricata, a Trans-Himalayan food crop having antioxidant and anticancer potential

Autor: Alka Choudhary, Raj Kumar, Ravi Bihari Srivastava, Sunil Kumar Surapaneni, Kulbhushan Tikoo, Inder Pal Singh
Jazyk: angličtina
Rok vydání: 2015
Předmět:
Zdroj: Journal of Functional Foods, Vol 16, Iss , Pp 183-193 (2015)
Druh dokumentu: article
ISSN: 1756-4646
DOI: 10.1016/j.jff.2015.04.013
Popis: The root of Rhodiola imbricata, a Trans Himalayan food crop is known for its antioxidant and adaptogenic properties. Four new compounds (7, 11, 12 and 15) together with known phenolic glycosides (10, 13–14, 16–19) and other phenolics (1–6, 8–9) were isolated from the ethyl acetate extract of the roots of R. imbricata. The structures of isolated molecules were established by spectroscopic techniques (ESI-HRMS, 1D and 2D NMR) and chemical methods. The compounds were evaluated for their antioxidant (radical scavenging, MTT antioxidant, linoleic acid peroxidation and reducing power assay) and anticancer activities against A-549 and MCF-7 cancer cell lines.
Databáze: Directory of Open Access Journals