Type 2 diabetes mellitus negatively affects the functional performance of 6-min step test in chronic heart failure: a 3-year follow-up study

Autor: Aldair Darlan Santos-de-Araújo, Daniela Bassi-Dibai, Izadora Moraes Dourado, Cássia da Luz Goulart, Renan Shida Marinho, Jaqueline de Almeida Mantovani, Gabriela Silva de Souza, Polliana Batista dos Santos, Meliza Goi Roscani, Shane A. Phillips, Audrey Borghi-Silva
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Diabetology & Metabolic Syndrome, Vol 16, Iss 1, Pp 1-12 (2024)
Druh dokumentu: article
ISSN: 1758-5996
DOI: 10.1186/s13098-024-01464-z
Popis: Abstract Background Type 2 diabetes mellitus (T2DM) and chronic heart failure (CHF) present a decrease in functional capacity due to the intrinsic nature of both pathologies. It is not known about the potential impact of T2DM on functional capacity when assessed by 6-min step test (6MST) and its effect as a prognostic marker for fatal and non-fatal events in patients with CHF. Objective to evaluate the coexistence of T2DM and CHF in functional capacity through 6MST when compared to CHF non-T2DM, as well as to investigate the different cardiovascular responses to 6MST and the risk of mortality, decompensation of CHF and acute myocardial infarction (AMI) over 36 months. Methods This is a prospective cohort study with 36 months of follow-up in individuals with T2DM and CHF. All participants completed a clinical assessment, followed by pulmonary function testing, echocardiography, and 6MST. The 6MST was performed on a 20 cm high step and cardiovascular responses were collected: heart rate, systemic blood pressure, oxygen saturation, BORG dyspnea and fatigue. The risk of mortality, acute myocardial infarction and decompensation of CHF was evaluated. Results Eighty-six participants were included. The CHF-T2DM group had a significantly lower functional capacity than the CHF non-T2DM group (p 0.05). Conclusion T2DM negatively affects the functional performance of 6MST in patients with CHF. Gender, ejection fraction (%), FEV1 (L) and T2DM itself negatively influence exercise performance.
Databáze: Directory of Open Access Journals
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