The 'dark' side of terlipressin: a case report of ischemic skin necrosis and review of literature

Autor:	Arpit Shastri, Sweta Rose, Nikhil Vojjala, Naveen Bhagat, Arka De
Jazyk:	angličtina
Rok vydání:	2023
Předmět:	Vasoconstrictors Variceal bleed Ischemic necrosis Gangrene Cirrhosis Surgery RD1-811 Diseases of the digestive system. Gastroenterology RC799-869
Zdroj:	Egyptian Liver Journal, Vol 13, Iss 1, Pp 1-4 (2023)
Druh dokumentu:	article
ISSN:	2090-6226
DOI:	10.1186/s43066-023-00273-9
Popis:	Abstract Background Terlipressin is a commonly used drug in cirrhotic patients with acute variceal bleed (AVB) due to its vasoconstrictor effects. Ischemic complications are uncommon adverse events associated with worse outcomes. Case presentation We present a case of alcohol-related cirrhosis, who was started on terlipressin for AVB. However, he developed bilateral lower limb gangrene with ischemic skin necrosis and ultimately succumbed to death. Conclusion Although ischemic adverse events are uncommon with terlipressin, it is important to be aware of these complications as they may be severe and potentially life threatening.
Databáze:	Directory of Open Access Journals
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