The Groebke–Blackburn–Bienaymé reaction in its maturity: innovation and improvements since its 21st birthday (2019–2023)
| Autor: | Cristina Martini, Muhammad Idham Darussalam Mardjan, Andrea Basso |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2024 |
| Předmět: | |
| Zdroj: | Beilstein Journal of Organic Chemistry, Vol 20, Iss 1, Pp 1839-1879 (2024) |
| Druh dokumentu: | article |
| ISSN: | 1860-5397 |
| DOI: | 10.3762/bjoc.20.162 |
| Popis: | The Groebke–Blackburn–Bienaymé (GBB) three-component reaction, discovered in 1998, is a very efficient strategy to assemble imidazo[1,2-a]-heterocycles starting from amidines, aldehydes and isocyanides. This review aims to exhaustively describe innovative aspects of this reaction achieved during the last five years, and classifies them into five categories: synthetic methods, building blocks, scaffolds, biological activities and physical properties. |
| Databáze: | Directory of Open Access Journals |
| Externí odkaz: |
|