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Objective To explore the clinical values of serum levels of cardiac troponin I (cTnI), cystatin C (CysC) and N-terminal B-type natriuretic propeptide (NT-proBNP) in patients with type IV cardiorenal syndrome (CRS) and examine their correlations with cardiac function. Methods From April 2020 to April 2022, thr relevant clinical data were retrospectively reviewed for 92 hospitalized patients of type IV CRS due to chronic renal insufficiency (CKD). Another 88 patients were selected as CKD group. The levels of cardiac troponin-I (cTnI), N-terminal B-type natriuretic propeptide (NT-proBNP), cystatin C (CysC) and echocardiographic results were collected and compared between two groups and those with different concentric functions. Results In CRS group, the levels of cTnI [0.026(0.013, 0.062)μg/L vs 0.010(0.005, 0.021)μg/L], NT-proBNP [15 292.0(2971.0, 35 000.0)μg/L vs 498.7(335.4, 1318.8)μg/L] and CysC [(4.48±1.73)mg/L vs (3.33±1.58)mg/L], left ventricular end diastolic dimension [(48.26±9.42)mm vs (45.65±5.28)mm], interventricular septal thickness at end-diastole [(11.52±1.76)mm vs (10.38±1.37)mm], left ventricular posterior wall thickness at end-diastole [(11.27±1.61)mm vs (10.21±1.29)mm] were significantly higher than those in nephrotic group. Meanwhile left ventricular ejection fraction in CRS group were lower than those in nephrotic group [(45.56±9.33)% vs (55.46±5.93%), P |
