Effect of nicotinic acid on the survival rate, and neurodegeneration of transgenic Drosophila melanogasterwith overexpression of human APP gene

Autor: O. I. Bolshakova, D. I. Rodin, S. I. Timoshenko, E. M. Latypova, S. V. Sarantseva
Jazyk: ruština
Rok vydání: 2013
Předmět:
Zdroj: Учёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова, Vol 20, Iss 3, Pp 14-17 (2013)
Druh dokumentu: article
ISSN: 1607-4181
2541-8807
Popis: Transgenic Drosophila melanogaster lines modeling the main neuromorphological markers of Alzheimer's disease were used to study the neuroprotective properties of nicotinic acid. Thirty days old flies treated with nicotinic acid showed better survival rate and reduced neurodegeneration.
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