A clinicopathological analysis of adrenal tumors in patients with history of extra-adrenal cancers

Autor: Lei Tan, Yunlin Ye, Kanghua Xiao, Xuelian Xu, Haitao Liang, Fufu Zheng, Zike Qin
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: BMC Cancer, Vol 19, Iss 1, Pp 1-6 (2019)
Druh dokumentu: article
ISSN: 1471-2407
DOI: 10.1186/s12885-019-6061-y
Popis: Abstract Background Adrenal tumors in patients with previous/synchronous extra-adrenal malignancy are diverse and are a dilemma in clinical practice. This study investigated the differentiation of adrenal malignant and benign tumors in these patients. Methods Data from patients with a pathological diagnosis of adrenal tumors were retrospectively retrieved from April 1991 to November 2015. Patients without extra-adrenal malignancy were excluded. Clinical and imaging characteristics, including sex, age, tumor size, tumor location, isolated lesion, time interval between the diagnosis of the two tumors and retrieved imaging diagnosis, were collected and analyzed. The selected patients were divided into 2 groups: those with primary or secondary malignancies (PSM) and those with primary benign tumors (PB). Chi-squared tests were used to evaluate differences between the two groups. Logistic regression was performed to explore potential risk factors related to the differentiation of PSM and PB, and a receiver operating characteristic (ROC) curve was used to evaluate their diagnostic values. Results Ninety-one patients were selected; 54 were male, and the median age was 56 years old. Between the groups of PSM and PB, sex (p = 0.004), age (p = 0.029), tumor size (p
Databáze: Directory of Open Access Journals
Nepřihlášeným uživatelům se plný text nezobrazuje