Approach to pancytopenia: From blood tests to the bedside

Autor: Shaun Chew, Majeed Kamangar
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Clinical Medicine, Vol 24, Iss 5, Pp 100235- (2024)
Druh dokumentu: article
ISSN: 1470-2118
DOI: 10.1016/j.clinme.2024.100235
Popis: Pancytopenia is an uncommon abnormality detected on a full blood count. Features of presentation tend to be non-specific, and are due to impaired functions of the cell lines involved. These can include fatigue, infection and bleeding. However, the aetiology of pancytopenia is extensive. This narrative review aims to provide a minimally invasive diagnostic algorithm for generalist clinicians to approach pancytopenia, including investigations into the underlying aetiology, and when a referral to the haematologist is warranted for further investigations such as bone marrow aspiration and trephine biopsy.
Databáze: Directory of Open Access Journals