Impact of microbial genome completeness on metagenomic functional inference

Autor: Raphael Eisenhofer, Iñaki Odriozola, Antton Alberdi
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: ISME Communications, Vol 3, Iss 1, Pp 1-5 (2023)
Druh dokumentu: article
ISSN: 2730-6151
DOI: 10.1038/s43705-023-00221-z
Popis: Abstract Inferring the functional capabilities of bacteria from metagenome-assembled genomes (MAGs) is becoming a central process in microbiology. Here we show that the completeness of genomes has a significant impact on the recovered functional signal, spanning all domains of metabolic functions. We identify factors that affect this relationship between genome completeness and function fullness, and provide baseline knowledge to guide efforts to correct for this overlooked bias in metagenomic functional inference.
Databáze: Directory of Open Access Journals
Nepřihlášeným uživatelům se plný text nezobrazuje