Stereodivergent dehydrative allylation of β-keto esters using a Ru/Pd synergistic catalyst

Autor: Thien Phuc Le, Shinji Tanaka, Masahiro Yoshimura, Kazuhiko Sato, Masato Kitamura
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-022-33432-4
Popis: α-Alkylation of β-keto esters is a frequently used reaction for carbon–carbon bond formation, but a general, stereoselective version of this reaction is challenging to realize. Here, the authors report a combined ruthenium and palladium catalytic system for the asymmetric dehydrative condensation between cinnamyl-type allylic alcohols and β-keto esters.
Databáze: Directory of Open Access Journals