How Well Do Results From Randomized Clinical Trials and/or Recommendations for Implantable Cardioverter‐Defibrillator Programming Diffuse Into Clinical Practice?Translation Assessed in a National Cohort of Patients With Implantable Cardioverter‐Defibrillators (ALTITUDE)

Autor: Niraj Varma, Paul Jones, Nicholas Wold, Edmond Cronin, Kenneth Stein
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 8, Iss 3 (2019)
Druh dokumentu: article
ISSN: 2047-9980
DOI: 10.1161/JAHA.117.007392
Popis: Background Inappropriate implantable cardioverter‐defibrillator programming can be detrimental. Whether trials/recommendations informing best implantable cardioverter‐defibrillator programming (high‐rate cutoff and/or extended duration of detection) influence practice is unknown. Methods and Results We measured reaction to publication of MADIT‐RIT (Multicenter Automatic Defibrillator Implantation Trial–Reduce Inappropriate Therapy; 2012) and the Consensus Statement (2015) providing generic programming parameters, in a national cohort of implantable cardioverter‐defibrillator recipients, using the ALTITUDE database (Boston Scientific). Yearly changes in programmed parameters to either trial‐specified or class 1 recommended parameters (≥185 beats per minute or delay ≥6 seconds) were assessed in parallel. From 2008 to 2017, 232 982 patients (aged 67±13 years; 28% women) were analyzed. Prevalence of MADIT‐RIT–specific settings before publication was
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