| Autor: |
Piskur Zoriana Ivanovna, Pylypiv Lesya, Shvets Olga, Sakhelashvili Manana, Kostyk Olga, Sakhelashvili-Bil Olga |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
Current Issues in Pharmacy and Medical Sciences, Vol 35, Iss 3, Pp 123-128 (2022) |
| Druh dokumentu: |
article |
| ISSN: |
2300-6676 |
| DOI: |
10.2478/cipms-2022-0023 |
| Popis: |
Pediatric tuberculosis is a health problem of special significance because it is a marker for current transmission of tuberculosis in society. The research aimed at analyzing the peculiarities of detection and course of pediatric extrapulmonary tuberculosis (EPTB) taking into account the profile of drug resistance. A retrospective study of medical charts of children with EPTB (n = 47; 1st group) and pulmonary tuberculosis (PTB) (n = 49; 2nd group) aged 0-15 for 2013-2020 has been conducted. 2 subgroups with EPTB were identified separately: resistant (EPRTB) (n = 23) and sensitive (EPSTB) (n = 24). Results and discussion. The frequency of EPTB was 9.8%. Tuberculosis of peripheral LN (40.5%), CNS (27.7%), bones and joints (23.4%) was significantly more often diagnosed, than other lesions. Almost half of children with EPTB had a miliary distribution. In 44.7% of children with EPTB contact with a patient with tuberculosis was not established. EPRTB was significantly more common among children under 1 and up to 3 years of age than EPSTB. The resistance to combination of HR (73.6%) was found more often than to HRES (10.5%), HRS, H and Z (5.3% each; p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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