Testing the Limit: Evaluating Drinking Water Arsenic Regulatory Levels Based on Adverse Pregnancy Outcomes in Bangladesh
| Autor: | Faye V. Andrews, Adam Branscum, Perry Hystad, Ellen Smit, Sakila Afroz, Mostofa Golam, Omar Sharif, Mohammad Rahman, Quazi Quamruzzaman, David C. Christiani, Molly L. Kile |
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| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Toxics, Vol 10, Iss 10, p 600 (2022) |
| Druh dokumentu: | article |
| ISSN: | 2305-6304 74525999 |
| DOI: | 10.3390/toxics10100600 |
| Popis: | (1) Background: Arsenic (As) is a common drinking water contaminant that is regulated as a carcinogen. Yet, As is a systemic toxicant and there is considerable epidemiological data showing As adversely impacts reproductive health. This study used data from a birth cohort in Bangladesh (2008–2011) to examine associations between drinking water As levels and reproductive outcomes. (2) Methods: Pregnant individuals (n = 1597) were enrolled at n = 1130) were propensity score matched to participants who experienced miscarriage (n = 132), stillbirth (n = 72), preterm birth (n = 243), and neonatal mortality (n = 20). Logistic regression was used to examine drinking water As recommendations of 50, 10, 5, 2.5, and 1 µg/L on the odds of adverse birth outcomes. (3) Results: The odds of miscarriage were higher for pregnant women exposed to drinking water ≥2.5 versus |
| Databáze: | Directory of Open Access Journals |
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