Reproducibility of the 75 g oral glucose tolerance test for the diagnosis of gestational diabetes mellitus in a sub-Saharan African population

Autor: Yvonne Nangeh Munang, Jean Jacques Noubiap, Celestin Danwang, Julius Dohbit Sama, Marcel Azabji-Kenfack, Jean Claude Mbanya, Eugene Sobngwi
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: BMC Research Notes, Vol 10, Iss 1, Pp 1-6 (2017)
Druh dokumentu: article
ISSN: 1756-0500
DOI: 10.1186/s13104-017-2944-7
Popis: Abstract Objective To evaluate the reproducibility of the 75 g oral glucose tolerance test and factors associated with non-reproducible results in Cameroonian pregnant women. Results Twenty-seven of the 84 participants (32.1%) who did the first oral glucose tolerance test were diagnosed with gestational diabetes mellitus. There was no difference between the means of the glycaemic responses at T0 (p = 0.64), T30 (p = 0.08), T60 (p = 0.86), T90 (p = 0.51), and T120 (p = 0.34) between the two oral glucose tolerance test. Age (p = 0.001) and BMI (p = 0.001) were significantly associated with non-reproducible results. The reproducibility of the oral glucose tolerance test in this study was 74.2%, and the kappa statistic’s 0.46. In conclusion, the results of the oral glucose tolerance test were reproducible in only 74.2% of pregnant women in this study. This highlights that a single oral glucose tolerance test for the diagnosis of gestational diabetes mellitus should be interpreted with caution.
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