Low temperature preparation of diopside nanoparticles: in-vitro bioactivity and drug loading evaluation

Autor: Ava sobhani, Esmaeil Salimi
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Druh dokumentu: article
ISSN: 2045-2322
DOI: 10.1038/s41598-023-43671-0
Popis: Abstract Bioactive diopside (CaMgSi2O6) nanoparticles have recently gained potential usefulness as bone replacement materials and nano vehicles for delivering therapeutics. The structural characteristics of this ceramic have found to be a key factor in bone bonding ability. To attain the desired product for 100% clinical success, it is important to realize the relationship between structure and biological activity. Synthesis of these nanoparticles via the solid-state method has been regarded as a low-cost and easy process in large-scale, but time consuming reactions and high temperature (≈ 1400 °C) are required. On the other side, the wet chemistry can overcome these drawbacks, whereas the presence of byproducts in the final powder has limited this method in large-scale production. The present document has represented a simple, fast and one-pot sol–gel approach for the synthesis of highly pure diopside nano-powders (
Databáze: Directory of Open Access Journals
Nepřihlášeným uživatelům se plný text nezobrazuje