Screening microbially produced Δ9-tetrahydrocannabinol using a yeast biosensor workflow

Autor: William M. Shaw, Yunfeng Zhang, Xinyu Lu, Ahmad S. Khalil, Graham Ladds, Xiaozhou Luo, Tom Ellis
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-022-33207-x
Popis: Microbial production of cannabinoids promises a cheaper and more sustainable route to these important therapeutic molecules, but strain improvement and screening is challenging. Here, the authors develop a yeast-based Δ9-tetrahydrocannabinol (THC) biosensor for screening microbial mutant libraries.
Databáze: Directory of Open Access Journals