Clinicopathologic and Molecular Analysis of Inflammatory Pseudotumor-Like Follicular/Fibroblastic Dendritic Cell Sarcoma: A Case Report and Review of Literature
| Autor: | Bryan MORALES-VARGAS, Kristin DEEB, Deniz PEKER |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: | |
| Zdroj: | Türk Patoloji Dergisi, Vol 37, Iss 3, Pp 266-272 (2021) |
| Druh dokumentu: | article |
| ISSN: | 1018-5615 1309-5730 |
| DOI: | 10.5146/tjpath.2021.01523 |
| Popis: | Inflammatory pseudotumor-like follicular/fibroblastic dendritic cell (FDC/FRC) sarcoma is an extremely rare neoplasm of the spleen associated with EBV and characterized by spindle cell morphology, dense mixed chronic inflammatory background, and a broad immunophenotypic profile often causing a diagnostic challenge for pathologists. The molecular features of FDC/FRC sarcoma are largely unknown due to a lack of comprehensive data. Here we present the results of next-generation sequencing and Single Nucleotide Polymorphism Copy Number array analysis in a case of FDC/FRC and review the literature. |
| Databáze: | Directory of Open Access Journals |
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