Relationship of neutrophil/lymphocyte ratio with cerebral small vessel disease and its common imaging markers

Autor:	Jiangping Cai, Xiaoyi Zeng, Xiaojin Huang, Hansheng Dong, Junyi Liu, Jie Lin, Meirong Xie, Xiaolan Wei
Jazyk:	angličtina
Rok vydání:	2024
Předmět:	cerebral small vessel disease enlarged perivascular spaces inflammation neutrophil/lymphocyte ratio white matter hyperintensity Immunologic diseases. Allergy RC581-607
Zdroj:	Immunity, Inflammation and Disease, Vol 12, Iss 4, Pp n/a-n/a (2024)
Druh dokumentu:	article
ISSN:	2050-4527
DOI:	10.1002/iid3.1228
Popis:	Abstract Background High neutrophil/lymphocyte ratio (NLR) is associated with poor prognosis in ischemic stroke. However, the role of NLR in cerebral small vessel disease (CSVD) is controversial. Herein, we evaluated the value of NLR in identifying CSVD and its relationship with the common imaging markers of CSVD. Methods A total of 667 patients were enrolled in this study, including 368 in the CSVD group and 299 in the non‐CSVD group. Clinical, laboratory, and imaging data were collected. The relationship of NLR with CSVD and common imaging markers of CSVD were analyzed with univariate and multivariate logistic regression analysis. The predictive value of NLR was assessed with the receiver operating characteristic curve. Results NLR (odds ratio [OR] = 1.929, 95% confidence interval [CI] = 1.599–2.327, p
Databáze:	Directory of Open Access Journals
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