| Autor: |
Rolando Barajas, Brionna Hair, Gabriel Lai, Melissa Rotunno, Marissa M. Shams-White, Elizabeth M. Gillanders, Leah E. Mechanic |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
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| Zdroj: |
PLoS ONE, Vol 16, Iss 12 (2021) |
| Druh dokumentu: |
article |
| ISSN: |
1932-6203 |
| Popis: |
Systems epidemiology offers a more comprehensive and holistic approach to studies of cancer in populations by considering high dimensionality measures from multiple domains, assessing the inter-relationships among risk factors, and considering changes over time. These approaches offer a framework to account for the complexity of cancer and contribute to a broader understanding of the disease. Therefore, NCI sponsored a workshop in February 2019 to facilitate discussion about the opportunities and challenges of the application of systems epidemiology approaches for cancer research. Eight key themes emerged from the discussion: transdisciplinary collaboration and a problem-based approach; methods and modeling considerations; interpretation, validation, and evaluation of models; data needs and opportunities; sharing of data and models; enhanced training practices; dissemination of systems models; and building a systems epidemiology community. This manuscript summarizes these themes, highlights opportunities for cancer systems epidemiology research, outlines ways to foster this research area, and introduces a collection of papers, “Cancer System Epidemiology Insights and Future Opportunities” that highlight findings based on systems epidemiology approaches. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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