Effect of urine reflex culturing on rates of cultures and infections in acute and long-term care

Autor: Chelsea S. Lynch, Andrea Appleby-Sigler, Jacqueline T. Bork, Rohini Davé, Kathy Agnes, Molly Sanikop, Doris Heath, Arlene F. Clark, Kimberly Claeys, Min Zhan, Daniel J. Morgan
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Antimicrobial Resistance and Infection Control, Vol 9, Iss 1, Pp 1-6 (2020)
Druh dokumentu: article
ISSN: 2047-2994
DOI: 10.1186/s13756-020-00762-1
Popis: Abstract Background Urine cultures are often positive in the absence of a urinary tract infection (UTI). Pyuria is generally considered necessary to diagnose a UTI. Problem Urine cultures are often positive in the absence of UTI leading to unnecessary antibiotics. Methods Quasi-experimental pre-post study of all patient urine cultures ordered in a VA acute care hospital, emergency department (ED), and two long-term care (LTC) facilities from August 2016 to August 2018. Urine cultures performed per 100 days were compared pre- (August 2016 to July 2017) versus post-intervention (August 2017 to August 2018) using interrupted time series negative binomial regression. Intervention We examined whether reflexing to urine culture only if a urinalysis (UA) found greater than 10 WBC/hpf decreased urine culturing. Results In acute-care, reflex culturing resulted in a 39% time series regression analysis adjusted decrease in the rate of cultures performed (pre-intervention, 3.6 cultures/100 days vs. Post-intervention, 1.8 cultures/100 days, p
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