| Autor: |
Caliskan Zehra Nur, Ozel Yetkin Merve, Baskol Mevlut, Baskol Gulden |
| Jazyk: |
angličtina |
| Rok vydání: |
2024 |
| Předmět: |
|
| Zdroj: |
Türk Biyokimya Dergisi, Vol 49, Iss 5, Pp 637-646 (2024) |
| Druh dokumentu: |
article |
| ISSN: |
1303-829X |
| DOI: |
10.1515/tjb-2022-0275 |
| Popis: |
Cholangiocarcinoma (CCA) is a highly heterogeneous biliary malignant tumor. Studies have demonstrated that JAK/STAT signaling is activated in many types of cancer. In addition, JAK/STAT is activated downstream of AXL, and the AXL receptor is activated by its ligand, GAS6. In this study, we investigated the anticarcinogenic effect of silibinin and its relationship with the GAS6/AXL ve JAK/STAT pathway in the human EGI-1 cell line. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
|
