Surgery for intestinal injuries in very preterm infants: a Norwegian population-based study with a new approach to disease classification

Autor: Claus Klingenberg, Ragnhild Støen, Kristin Bjørnland, Hans Jørgen Stensvold, Arild Rønnestad, Nina Clare Hapnes, Thorstein Sæter, Hans Jørgen Timm Guthe, Sissel Jennifer Moltu
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: BMJ Paediatrics Open, Vol 8, Iss 1 (2024)
Druh dokumentu: article
ISSN: 2399-9772
DOI: 10.1136/bmjpo-2024-002722
Popis: Objective To evaluate population-based data on very preterm infants (3 days after disease onset (n=14). High lactate values immediately prior to surgery was predominantly seen in acute NEC-extensive disease and associated with high mortality. Other laboratory values could not discriminate between acute NEC and FIP. Timing of surgery for acute NEC and FIP overlapped. Radiological absence of portal venous gas was typical in FIP. Most infants (62.5%) underwent a stoma formation at initial surgery. The overall survival rate was 67% for NEC and 77% for FIP.Conclusion NEC cases have different presentation and prognosis depending on the extent of bowel affected. Revised classifications for intestinal injuries in preterm infants may improve prognostication and better guide therapy.
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