Changes in a functional condition of prooxidant system in guinea pigs’ blood in experimental allergic alveolitis and their correction with thiotriazolin

Autor: Oksana Volodumurivna Sadljak, Zoryana Ljubomurivna Solvar, Mariana Ljubomurivna Baida
Jazyk: English<br />Spanish; Castilian<br />Polish<br />Russian<br />Ukrainian
Rok vydání: 2018
Předmět:
Zdroj: Journal of Education, Health and Sport, Vol 8, Iss 1, Pp 186-190 (2018)
Druh dokumentu: article
ISSN: 2391-8306
DOI: 10.5281/zenodo.1182648
Popis: The study shows that significant elevation of conjugated dienes and malondialdehude in the blood of guinea pigs depend on experimental allergic alveolitis duration was detected. Oxidative stress can arises from overproduction of reactive oxygen species(ROS) by metabolic reactions that use oxygen. ROS also affects the expression of several genes by upregulation of redox-sensitive transcription factors. Regulation of redox state is critical for cell viability, activation, proliferation, and organ function. Corrective effect of thiotriazoline on these indicators have demonstrated .
Databáze: Directory of Open Access Journals