Research progress of drugs targeting ferroptosis for the treatment of non-alcoholic fatty liver disease

Autor: HAO Dandan, ZHANG Lei, BAI Chunying
Jazyk: čínština
Rok vydání: 2023
Předmět:
Zdroj: Jichu yixue yu linchuang, Vol 43, Iss 8, Pp 1317-1321 (2023)
Druh dokumentu: article
ISSN: 1001-6325
DOI: 10.16352/j.issn.1001-6325.2023.08.1317
Popis: Emerging evidence indicates that ferroptosis, an iron-dependent form of regulated cell death, plays a critical role in the pathological progression of non-alcoholic fatty liver disease (NAFLD). Ferroptosis involves in the pathogenesis of NAFLD and drugs targeting at ferroptosis by its inhibitors can alleviate the progression of NAFLD both in vitro and in vivo. Pharmacological inhibition of ferroptosis might be a potential strategy of NAFLD treatment.
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