| Autor: |
Emily G. Hurley, Fangbai Sun, Heping Zhang, Alex J. Polotsky, Julie Sroga Rios |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
Women's Health Reports, Vol 3, Iss 1, Pp 957-963 (2022) |
| Druh dokumentu: |
article |
| ISSN: |
2688-4844 |
| DOI: |
10.1089/WHR.2022.0080 |
| Popis: |
Background: The optimal protocol for minimal stimulation in vitro fertilization (IVF) has yet to be established. This study aims to determine if the use of gonadotropin-releasing hormone (GnRH) antagonist during minimal stimulation improves outcomes. Materials and Methods: All cycles designated as minimal stimulation from 2014 to 2016 from the Society for Assisted Reproductive Technology Clinic Online Reporting System were identified. Cycles in which GnRH antagonist was administered (n?=?5984) were compared to those that did not receive it (n?=?7066). Wilcoxon's rank-sum test and chi-square test were used to analyze continuous and categorical variables. Results: A total of 6750 patients undergoing 13,050 cycles were included. GnRH antagonist use was associated with a significantly higher total gonadotropin dosage (median 975.0 [interquartile range, IQR, 600.0, 1575.0] vs. median 660.0 [IQR 375.0, 975.0], p?0.001), lower cycle cancelation rate (11.3% vs. 13.6%, p?
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| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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