Autor: |
Pierre-Olivier Estève, Sagnik Sen, Udayakumar S. Vishnu, Cristian Ruse, Hang Gyeong Chin, Sriharsa Pradhan |
Jazyk: |
angličtina |
Rok vydání: |
2022 |
Předmět: |
|
Zdroj: |
Communications Biology, Vol 5, Iss 1, Pp 1-18 (2022) |
Druh dokumentu: |
article |
ISSN: |
2399-3642 |
DOI: |
10.1038/s42003-022-04241-8 |
Popis: |
SET8 is post-translationally poly ADPribosylated by PARP1 on several lysine residues, leading to SET8 degradation via ubiquitylation and genome-wide aberrant H4K20 methylation. |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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