Features of the immune disbalance during various clinico-pathogenetic variants of acute progressive pulmonary tuberculosis
| Autor: | O. V. Voronkova, O. I. Urazova, V. V. Novitsky, Ye. G. Churina, R. R. Khasanova, I. O. Naslednikova, O. V. Filinyuk, V. A. Serebryakova, Yu. V. Kolobovnikova, Ye. L. Nikulina, N. P. Pirogova, I. V. Berezko |
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| Jazyk: | English<br />Russian |
| Rok vydání: | 2010 |
| Předmět: | |
| Zdroj: | Бюллетень сибирской медицины, Vol 9, Iss 3, Pp 42-50 (2010) |
| Druh dokumentu: | article |
| ISSN: | 1682-0363 1819-3684 |
| DOI: | 10.20538/1682-0363-2010-3-42-50 |
| Popis: | In article the data, concerning features of cellular composition, proliferative activity and cytokines production of peripheral blood lymphocytes is presented in patients with various clinico-pathogenetic variants of pulmonary tuberculosis: drag-sensitive and drug-resistant infiltrative, disseminated, fibrous-cavernous. It is established that the extensive destructive tuberculosis without dependence from the clinical form of disease is accompanied by the expressed insufficiency of the cellular-mediated mechanisms of immunological resistance both to drag-sensitive, and to drug-resistant M. tuberculosis against quantitative prevalence of B-lymphocytes and intensity of their functional activity. |
| Databáze: | Directory of Open Access Journals |
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