Long-Term Outcomes of Birdshot Chorioretinopathy Treated with Corticosteroids: A Case Reports

Autor: Dino Ferracci, Thibaud Mathis, Antoine Gavoille, Mathieu Gerfaud-Valentin, Arthur Bert, Meriem Hafidi, Philippe Denis, Olivier Loria, Laurent Kodjikian, Pascal Sève
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Journal of Clinical Medicine, Vol 12, Iss 16, p 5288 (2023)
Druh dokumentu: article
ISSN: 2077-0383
DOI: 10.3390/jcm12165288
Popis: Purpose: To report the progression of patients diagnosed with birdshot chorioretinopathy (BSCR) initially treated with corticosteroids. Methods: We included 39 BSCR patients that were followed for ≥1 year. We analyzed their progression under treatment after 1, 3, 6 months, 1 year, and at the end of follow-up. In order to determine the efficiency of initial loading doses, patients were classified into two groups according to their initial treatment: methylprednisolone followed by prednisone (n = 28) and prednisone alone (n = 11). Results: At the end of follow-up, 31/39 (79.5%) patients had reached inflammation control. Thirteen out of 28 (46.4%) and 6/11 (54.5%) patients were treated exclusively with corticosteroids, and 18/19 (94.7%) of them had reached inflammation control at the end of follow-up; their mean (range) corticosteroid dose was 3.5 (0–10) mg/day. Conclusions: We found that the prolonged corticosteroid therapy treatment strategy resulted in inflammation control in half of BSCR patients. This control was maintained with low doses of cortisone, usually
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