Comparative study on epidemiological and etiological characteristics of patients with acute diarrhea with febrile or non-febrile symptoms in China

Autor: Tao Wang, Gang Wang, Chun-Xi Shan, Yan-Qun Sun, Xiang Ren, Lin-Jie Yu, Yi-Fei Wang, Sheng-Hong Lin, Xiao-Ai Zhang, Hao Li, Cui-Hong Zhang, Meng-Jie Geng, Wei-Zhong Yang, Li-Ping Wang, Wei Liu, Li-Qun Fang
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Infectious Diseases of Poverty, Vol 12, Iss 1, Pp 1-12 (2023)
Druh dokumentu: article
ISSN: 2049-9957
23849576
DOI: 10.1186/s40249-023-01108-w
Popis: Abstract Background Acute diarrhea with fever can potentially represent a more severe form of the disease compared to non-febrile diarrhea. This study was to investigate the epidemiological characteristics and enteric pathogen composition of febrile-diarrheal patients, and to explore factors including pathogens associated with fever by age group. Methods A nationwide surveillance study of acute diarrheal patients of all ages was conducted in 217 sentinel hospitals from 31 provinces (autonomous regions or municipalities) in China between 2011 and 2020. Seventeen diarrhea-related pathogens, including seven viruses and ten bacteria, were investigated and their association with occurrence of fever symptoms was assessed using multivariate logistic analysis. Results A total of 146,296 patients with acute diarrhea (18.6% with fever) were tested. Th diarrheal children below 5 years had the highest frequency of fever (24.2%), and related to significantly higher prevalence of viral enteropathogens (40.2%) as compared with other age groups (P
Databáze: Directory of Open Access Journals
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