Intravascular schwannoma as an extremely unusual cause of vein obstruction: a case report
| Autor: | Luis Miguel Chinchilla-Tábora, Beatriz Segovia Blázquez, José María Sayagués, Marta Rodríguez González, Joaquín González-Rivero, José Antonio Muñoz León, Andrea Beatriz Jiménez Pérez, Idalia González Morais, Diego Bueno-Sacristán, María Dolores Ludeña |
|---|---|
| Jazyk: | English<br />Korean |
| Rok vydání: | 2024 |
| Předmět: | |
| Zdroj: | Journal of Pathology and Translational Medicine, Vol 58, Iss 5, Pp 249-254 (2024) |
| Druh dokumentu: | article |
| ISSN: | 2383-7837 2383-7845 |
| DOI: | 10.4132/jptm.2024.05.15 |
| Popis: | The blood vessel lumen is an extremely rare location for a benign peripheral nerve sheath tumor like schwannoma. Less than 10 cases have been previously reported. In this report, we present a case of a 68-year-old woman who had a soft tissue nodule at the posterior calf of her left leg during a physical examination. Pathological examination was performed after complete surgical excision. The patient underwent follow-up for 12 months after surgery without evidence of recurrence or any other complication. This is the first case of intravascular schwannoma reported as a cause of vein obstruction. Microscopically, the tumor was composed of Schwann spindle cells that were immunoreactive for S100 protein and SOX10. This tumor was surrounded by a well-defined vascular smooth muscle wall. Prospective series are required to improve the knowledge on the underlying mechanisms of intravascular schwannoma development. |
| Databáze: | Directory of Open Access Journals |
| Externí odkaz: |
|