| Autor: |
Miguel F. Gago, Darya Yelshyna, Estela Bicho, Hélder David Silva, Luís Rocha, Maria Lurdes Rodrigues, Nuno Sousa |
| Jazyk: |
angličtina |
| Rok vydání: |
2016 |
| Předmět: |
|
| Zdroj: |
Dementia and Geriatric Cognitive Disorders Extra, Vol 6, Iss 2, Pp 252-267 (2016) |
| Druh dokumentu: |
article |
| ISSN: |
1664-5464 |
| DOI: |
10.1159/000447124 |
| Popis: |
Background/Aims: Alzheimer's disease (AD) patients have an impaired ability to quickly reweight central sensory dependence in response to unexpected body perturbations. Herein, we aim to study provoked compensatory postural adjustments (CPAs) in a conflicting sensory paradigm with unpredictable visual displacements using virtual reality goggles. Methods: We used kinematic time-frequency analyses of two frequency bands: a low-frequency band (LB; 0.3-1.5 Hz; mechanical strategy) and a high-frequency band (HB; 1.5-3.5 Hz; cognitive strategy). We enrolled 19 healthy subjects (controls) and 21 AD patients, divided according to their previous history of falls. Results: The AD faller group presented higher-power LB CPAs, reflecting their worse inherent postural stability. The AD patients had a time lag in their HB CPA reaction. Conclusion: The slower reaction by CPA in AD may be a reflection of different cognitive resources including body schema self-perception, visual motion, depth perception, or a different state of fear and/or anxiety. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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