Cefiderocol and Intraventricular Colistin for Ventriculitis due to an Extensively Drug-Resistant Pseudomonas Aeruginosa

Autor: Melo e Silva João, Oliveira Diogo, Louro João A., Monteiro Elisabete
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: The Journal of Critical Care Medicine, Vol 10, Iss 2, Pp 183-187 (2024)
Druh dokumentu: article
ISSN: 2393-1817
DOI: 10.2478/jccm-2024-0020
Popis: Rheumatoid arthritis, an inflammatory rheumatic disease predominantly affecting small limb joints, frequently compromises the cervical spine, resulting in spinal instability and the potential surgical necessity. This may result in severe complications, such as ventriculitis, often associated with a high mortality rate and multidrug-resistant organisms. A major challenge lies in achieving therapeutic antimicrobial concentrations in the central nervous system.
Databáze: Directory of Open Access Journals