The role of bronchoscopy in patients with SARS-CoV-2 pneumonia
| Autor: | Marisol Arenas-De Larriva, Roberto Martín-DeLeon, Blanca Urrutia Royo, Iker Fernández-Navamuel, Andrés Gimenez Velando, Laura Nuñez García, Carmen Centeno Clemente, Felipe Andreo García, Albert Rafecas Codern, Carmen Fernández-Arias, Virginia Pajares Ruiz, Alfons Torrego Fernández, Olga Rajas, Gorane Iturricastillo, Ricardo Garcia Lujan, Lorena Comeche Casanova, Albert Sánchez-Font, Ricardo Aguilar-Colindres, Roberto Larrosa-Barrero, Ruth García García, Rosa Cordovilla, Ana Núñez-Ares, Andrés Briones-Gómez, Enrique Cases Viedma, José Franco, Javier Cosano Povedano, Manuel Luis Rodríguez-Perálvarez, Jose Joaquin Cebrian Gallardo, Manuel Nuñez Delgado, María Pavón-Masa, Maria del Mar Valdivia Salas, Javier Flandes |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: | |
| Zdroj: | ERJ Open Research, Vol 7, Iss 3 (2021) |
| Druh dokumentu: | article |
| ISSN: | 2312-0541 23120541 |
| DOI: | 10.1183/23120541.00165-2021 |
| Popis: | Background The role of bronchoscopy in coronavirus disease 2019 (COVID-19) is a matter of debate. Patients and methods This observational multicentre study aimed to analyse the prognostic impact of bronchoscopic findings in a consecutive cohort of patients with suspected or confirmed COVID-19. Patients were enrolled at 17 hospitals from February to June 2020. Predictors of in-hospital mortality were assessed by multivariate logistic regression. Results A total of 1027 bronchoscopies were performed in 515 patients (age 61.5±11.2 years; 73% men), stratified into a clinical suspicion cohort (n=30) and a COVID-19 confirmed cohort (n=485). In the clinical suspicion cohort, the diagnostic yield was 36.7%. In the COVID-19 confirmed cohort, bronchoscopies were predominantly performed in the intensive care unit (n=961; 96.4%) and major indications were: difficult mechanical ventilation (43.7%), mucus plugs (39%) and persistence of radiological infiltrates (23.4%). 147 bronchoscopies were performed to rule out superinfection, and diagnostic yield was 42.9%. There were abnormalities in 91.6% of bronchoscopies, the most frequent being mucus secretions (82.4%), haematic secretions (17.7%), mucus plugs (17.6%), and diffuse mucosal hyperaemia (11.4%). The independent predictors of in-hospital mortality were: older age (OR 1.06; p |
| Databáze: | Directory of Open Access Journals |
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