Autor: |
Hongwei Zhang, Xiaoyu Zheng, Zian Yan, Lijun Guo, Yuan Zheng, Dawu Zhang, Xiaochang Ma |
Jazyk: |
angličtina |
Rok vydání: |
2024 |
Předmět: |
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Zdroj: |
Frontiers in Cardiovascular Medicine, Vol 11 (2024) |
Druh dokumentu: |
article |
ISSN: |
2297-055X |
DOI: |
10.3389/fcvm.2024.1439699 |
Popis: |
ObjectiveTo investigate the causal relationship between 233 newly reported metabolites and coronary atherosclerosis through Mendelian randomization analysis.MethodsFive different methods were used to perform Mendelian randomization analysis on the 233 metabolites and coronary atherosclerosis, with inverse variance weighting as the primary result, supplemented by other methods.ResultsThe analysis identified that certain metabolites increase the susceptibility risk of coronary atherosclerosis, including: Total fatty acids (OR = 1.40, 95% CI: 1.28–1.53, P |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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