| Autor: |
Yee Rae Park, Eu Jeen Yang, Ju Kyung Hyun, Ina Jeong, In-Sook Kim, Young Tak Lim |
| Jazyk: |
English<br />Korean |
| Rok vydání: |
2023 |
| Předmět: |
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| Zdroj: |
Clinical Pediatric Hematology-Oncology, Vol 30, Iss 2, Pp 70-74 (2023) |
| Druh dokumentu: |
article |
| ISSN: |
2233-5250 |
| DOI: |
10.15264/cpho.2023.30.2.70 |
| Popis: |
Isolated extramedullary relapse (EMR) after allogeneic hematopoietic stem cell transplantation (allo-HSCT) in acute myeloid leukemia (AML) is relatively rare and the clinical significance is still not well characterized, particularly in children. During or after chemotherapy, an uncommon event termed lineage switch, in which the lineage at onset of leukemia converts to another lineage at a later time, is observed in a subset of leukemia patients, but it is a rare event. We report a 10-year-old boy with isolated mediastinal EMR after allo-HSCT for AML who subsequently experienced BM relapse with the cell lineage switching from AML to T-cell acute lymphoblastic leukemia. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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