Comparison of three methods based on endoscopic gastric biopsies for diagnosis of Helicobacter pylori active infection in a clinical setting
| Autor: | Gabriel Arismendi-Morillo, Ileana Hernández, Edgardo Mengual, Alisbeth Fuenmayor, Gisela Romero, Maribel Lizarzábal |
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| Jazyk: | angličtina |
| Rok vydání: | 2011 |
| Předmět: | |
| Zdroj: | Arquivos de Gastroenterologia, Vol 48, Iss 3, Pp 190-194 (2011) |
| Druh dokumentu: | article |
| ISSN: | 1678-4219 0004-2803 68721692 |
| DOI: | 10.1590/S0004-28032011000300007 |
| Popis: | CONTEXT: The correct diagnosis and effective treatment of Helicobacter pylori gastric infection are essential in controlling this infection. OBJECTIVE: To compare the diagnostic value of three tests based in endoscopic gastric biopsies histopathological evaluation with hematoxylin-eosin (H-E) staining, urease rapid test and microbiological culture for detecting Helicobacter pylori active infection, in order to make recommendations for daily clinical practice. METHODS: Gastric biopsies from 115 adult patients (85 female/30 male) were obtained by upper gastrointestinal endoscopy and studied by histopathological evaluation with H-E (antrum-corpus), urease test in 2 hours (antrum) and microbiological culture (antrum). RESULTS: Helicobacter pylori active infection was diagnosed in 67% of patients. Helicobacter pylori active infection was detected by histopathological evaluation with H-E, urease test and microbiological culture in 87%, 79% and 70% of the positive cases, respectively. There were significant differences when histopathological evaluation with H-E and urease test rapid test when compared with microbiological test (P |
| Databáze: | Directory of Open Access Journals |
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