Effectiveness of polyherbal formulations for the treatment of type 2 Diabetes mellitus - A systematic review and meta-analysis

Autor: Renuka Suvarna, Revathi P. Shenoy, Basavaraj S. Hadapad, Anupama V. Nayak
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Journal of Ayurveda and Integrative Medicine, Vol 12, Iss 1, Pp 213-222 (2021)
Druh dokumentu: article
ISSN: 0975-9476
DOI: 10.1016/j.jaim.2020.11.002
Popis: Background: The mortality and morbidity rate of diabetes patients is increasing worldwide which requires an ideal treatment to prevent the disease worsening. Traditional medicine is gaining more attention in diabetes due to its efficacy and safety. We, therefore performed a systematic review study of clinical trials to assess the comparative effect of polyherbal formulations in type 2 Diabetes mellitus. Objectives: To find the effectiveness of polyherbal formulations in blood sugar and lipid level for type 2 Diabetes mellitus. Material and methods: PubMed, Scopus and CINAHL databases for clinical trials investigating the effect of polyherbal formulations in Type 2 Diabetes mellitus patients were searched. Meta-analysis of eligible trials was conducted employing Revman 5.2 software. Results: Fourteen randomized controlled trials were found eligible for meta-analysis. Meta-analysis of findings showed a significant effect of polyherbal formulations on blood sugar level compared to control group. The estimated standard mean changes at 95% confidence interval, following polyherbal formulations treatment were −0.59, (−0.91 to – 0.27) mg/dL; for fasting blood sugar(p
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